The product brief introduction

Nesiritide Acetate (BNP-32)  CAS NO: 114471-18-0

Nesiritide is a synthetic human brainnatriureticpeptide (BNChemicalbookP) obtained from Escherichiacoli using recombinant DNA technology, and its effect is very similar to that of human BNP. It contains a 32-amino acid polypeptide, which is joined by a disulfide bond between its l0 and 26th amino acid (both cysteine), forming a ring containing l7 amino acids.

Nesiritide acts after binding to natriuretic peptide A and B receptors. In addition to increasing the production of cGMP, nesilitide also decreased the activity of renin-angiotensin system (RAS) and sympathetic nerve. It has definite dilating effect on the whole body arteriole and venule. It can significantly reduce the pulmonary capillary chock pressure and Chemicalbook right atrial pressure J, and reduce cardiac preload in heart failure. Nesiritide can also significantly reduce the total peripheral vascular resistance, so as to reduce the cardiac afterload in heart failure. It can increase cardiac index, and its mechanism is related to reducing cardiac afterload. It has specific dilating effect on coronary artery. It also has the effect of reducing myocardial oxygen consumption.

Product Name:	Nesiritide Acetate (BNP-32)
CAS:	114471-18-0
molecular formula:	C143H244N50O42S4
molecular weight	3464.04
EINECS	253-368-1
solubility:	≥206.6 mg/mL in DMSO
structural formula

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Professionalism of production: We have many years of experience in the production of peptide products to ensure the stable and reliable quality of each batch of peptide products.

The product quality has passed the professional production process and quality inspection, and the purity is more than 99%;

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Company profile

SaiWanTe (Shanghai) New Material Technology Co.,Ltd , located in shanghai ,China. It is specialized in the R&D, production and sales of chemical raw matereials, cosmetic additives, food additives and API-Active Pharmaceutical Ingredients . It is a high-tech enterprise in China. Its products are widely used in the health industry, medical beauty, green agriculture, bio-medicine and other fields.

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2) You can also send us the specifications or your requirements, and we will customize the product for you.

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